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Gliomas manipulate glutamate transporter expression and function to alter glutamate homeostasis in the brain, which supports their own growth, invasion, and survival

For peptides, a "soft" ionization technique like Electrospray Ionization (ESI) is used, which transfers the peptide molecules into the gas phase as ions without fragmenting them

4,11,15 Inflammatory responses mediated by proinflammatory cytokines and pathways, such as nuclear factor kappa B (NF-B) and Toll-like receptor 4 (TLR4), worsen the condition by amplifying oxidative stress and hindering neuronal repair

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In terms of report quality, it should be noted that there was an inconsistency in number of dropouts in the placebo group between text and the flowchart