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Extensive evidences have highlighted the interaction between mitochondrial metabolic dysfunction, mtDNA damage, mitochondrial dynamics disorders, mitophagy dysregulation, and oxidative stress, while targeting oxidative stress represents a promising strategy for combating mitochondria diseases

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Regarding the impact of NIF on MTX-induced intestinal injury, NIF exhibited potent antioxidant benefits against MTX-provoked intestinal injury by controlling PPAR-, SIRT1, and Nrf2 redox-sensitive signals expression (Abd-Alhameed et al

Davis, James F

Another small study reported less stiffness in the arteries, a factor that contributes to high blood pressure

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