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L-carnitine used to treat hyper-ammonia in children with urea-cycle enzyme deficiencies26 and valproate-induced hyper-ammonia.27 The protec tive effects of L-carnitine are centrally mediated by activation of metabotropic Glu receptors at the level of brain ammonia uptake and/or mitochondrial energy metabolism

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Assessments of both the current and past extent of skin lesions were based on the Wallace rule of nines 30

Epilepsy is a neurological disorder characterized by abnormal discharge of neurons leading to increased excitability