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The conditions frequency varies worldwide, influenced by ancestry and history

Further development of in vitro and in vivo models is essential to evaluate mitochondrial transfers long-term effects and ensure mitochondrial functionality post-transfer, facilitating exploration of the therapeutic benefits of this phenomenon in aged T cells (Fig

This review serves as a valuable resource for researchers aiming to develop new formulations, yet future studies must prioritize rigorous pharmacokinetic evaluations and long-term toxicity profiles to ensure patient safety