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However, it also heavily influences the flow of blood through the microcirculation, where blood acts as a thixotropic fluid, somewhat like toothpaste, flowing under increased pulses of blood pressure, then reverting to a semi-solid gel

Hypoxia and inflammation activate p53 via phosphorylation

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Interestingly, -synuclein and other associated proteins like DJ-1, parkin, and LRRK2 play a perilous role in the activation of microglia (Calopa et al