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MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis

Several complex I inhibitors have been evaluated clinically and discontinued due to neurotoxicity and adverse side effects (IACS-010759, Tamoxifen, Piericidin A, Phenformin) (76, 77)

Abstract Nicotinamide adenine dinucleotide (NAD + ) is a coenzyme involved in a plethora of physiological reactions, with a key relevance in supporting mitochondrial function

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