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Taking into account the complexity of these multiple intra- and interconnections, the circadian clock emerges as a crucial regulator of key physiological processes and its misalignment as potential triggering factor and/or pathological outcome in several human diseases, such as cancer and inflammatory diseases

Conversely, nitric oxide (NO) and prostaglandin E 2 (PGE 2 ) produced by iNOS and COX-2 during neuroinflammation, contribute to increased ROS levels [68]

These nutrients are easily absorbed in the liposomal form