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Microsomes retain most of the morphologic and functional characteristics of the intact membranes, including the rough and smooth surface features of the rough (ribosome-studded) and smooth (no ribosomes) endoplasmic reticulum

Li L, Pan G, Fan R, Li D, Guo L, Ma L et al (2022) Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats

Upon release, Nrf2 translocates to the nucleus and binds to the antioxidant response element (ARE) located in the promoter of genes coding for antioxidant/detoxifying enzymes and scavengers

It also interacts with the p53 pathway, limiting apoptosis of perihematomal neurons 20

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However, a subgroup analysis (as part of the meta-analysis) found significantly lower vitamin D levels in those with recurring BPPV compared to those with non-recurring BPPV