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Multiple sclerosis and glutamate excitotoxicity

10.1136/bmjopen-2013-004365 25 MasarwaR.LevineH.GorelikE.ReifS.PerlmanA.MatokI

Journal of Paediatrics and Child Health 2014;50(9):7215

doi: 10.3390/ijms24119736 119 RyuK

Pro-inflammatory cytokine receptors are highly aggregated in regions associated with cognitive functioning such as the hippocam-pus.4546 Pro-inflammatory cytokines and their receptors may inhibit neurogenesis and impair cognitive function.4748 Numerous reports have supported the idea that several pro-inflammatory cytokines affect neurogenesis