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Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia [Internet]

Some adopt a 5 days on, 2 days off weekly schedule as an alternative to full breaks

When exposed to zinc in vitro , DCs derived from bone marrow exhibited a tolerogenic profile, characterized by reduced surface MHC-II expression and increased levels of tolerogenic markers such as Programmed Death-Ligand (PD-L) 1, PD-L2 and the tryptophan degrading enzyme, Indoleamine 2,3-dioxygenase (IDO)