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Description

Outcome measurements

Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections

Altme, S., Laanpere, M., Campoy, C

doi: 10.1128/jb.178.14.4301-4305.1996 35 NewtonG

Second, it is able to induce the combination of ,-unsaturated ketones and GSH through the nucleophilic addition reaction, depleting GSH and reducing the amount of GSH available to combine with chemotherapeutic agents, thus producing an overall GST-inhibitory effect by sensitizing a cell to chemotherapeutic agents