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To solubilize IBs a combination of denaturants such as Sodium do-decyl sulphate (SDS), urea and organic solvents such as 40% ( v/v ) 1-Propanol and 20% ( v/v ) 2-Butanol in an acidic pH (range of 23) are used [58]

The suppression of glutathionylation is important in FUS-induced neurodegenerative diseases

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Epigenetic mechanisms, particularly those involving DNA and RNA methylation, are increasingly recognized as central to the pathogenesis of ankylosing spondylitis (AS) and related bone disorders