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Ma Y, Trump DL, Johnson CS

Studies have demonstrated a 40% increase in LPL activity and triglyceride hydrolysis with hesperidin treatment in adipose tissue models

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However, a limitation of this work is the lack of direct measurement of these lipoic modifications in cells

It has been demonstrated that NRF2 over-activation may be therapeutically beneficial for ameliorating RA owing to its anti-inflammatory and anti-oxidative activity associated with limiting cytokine production, cartilage-matrix degradation, and bone resorption 63

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