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To replenish intracellular GSH, cells synthesize GSH in a two-step metabolic pathway centred on the rate-limiting enzyme glutamate cysteine ligase (GCL), which is composed of a catalytic (GCLC) and a regulatory or modifier (GCLM) subunit, and the GSH synthetase (GS) 22

Vitr Cell Dev Biol Anim

Treatment of lactic acidosis with dichloroacetate in dogs

Mar Ecol Prog Ser 243:133141 Gowland FC, Boyle PR, Noble LR (2003) Asymmetry in the embryonic chromatophore pattern of the squid Loligo forbesi (Mollusca: Cephalopoda): a proxy for development instability