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For a multitude of reasons, including the physical burden of disease, obesity-related comorbidities, patient quality of life, and economic expenditures, it is imperative to develop effective tools to treat obesity

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In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg