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Therefore, there remains a major unmet need for alternative model systems, which are more relevant to humans and which can provide improved prediction of risk of liver injury in humans

Tang, N., Li, D., Wang, X., & Sun, Z

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Moreover, TMZ-mediated O6-methyl (O 6 -Me) guanine damage was shown to trigger an elevation in MMR, mediated by MLH1 and DNA MMR protein MSH2 (MSH2)