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Many people try over-the-counter painkillers or avoid triggers, but the pain often returns and may worsen over time

Usually, people have a limited understanding of medical vocabulary and hence are not exposed to the language being used by healthcare professionals

Although the exact cause of subnormal serum aminotransferase levels in CKD remains controversial, possible reasons are the severity of the impairment of renal function caused by glomerular dysfunction, pyridoxine deficiency and/or the presence of an inhibitory substance in uremia

30 This may be related to a mix of the biological (reduced tissue health) and psychological/behavioural effects

Veterinary J (2017) 221:5661