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This structure is like a well-organized toolbox, where every tool has its place for ready use

Silencing of ABCD1 and ABCD2 in mouse primary astrocytes in vitro caused an increase in C 26:0 /C 22:0 ratio as well as in the levels of C 26:0 compared with control and scrambled RNA (ScrRNA)-treated astrocytes

Given that the addition of an anionic activator like Pi was necessary for enzyme activity, it was assumed that the dimer-to-tetramer transition for the glutaminase enzymes was responsible for catalysis

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