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Hematol Am Soc Hematol Educ Program 2014:432437 Centers for Disease Control and Prevention (CDC)

The levels of plasma homocysteine may also elevate in folic acid or vitamin B6 deficiency, but the increase in MMA always indicates a poor status of vitamin B12 (the only other reason that explains the increased levels of MMA is renal insufficiency)

However, about 12 hepatic CYPs are responsible for the metabolism of the majority of drugs and other xenobiotics (approximately 93% of the drug metabolism) [1, 4]

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Mechanistic modeling of cyclic voltammetry: a helpful tool for understanding biosensor principles and supporting design optimization