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Description

The hMPV F polypeptide or nucleic acid molecule of any one of claims 8-14, wherein said prefusion F polypeptide further comprises an Fo cleavage site mutation comprising amino acid substitutions Q100R and S101 R, replacing glutamine at amino acid position 100 of SEQ ID NO: 1 with arginine, and replacing serine at amino acid position 101 of SEQ ID NO: 1 with arginine

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