curcumin glutathione s transferase synergistically enhances the efficacy of gemcitabine against gemcitabine-resistant cholangiocarcinoma via the targeting LAT2/glutamine pathway induction of glutathione s-transferase activity

Excessive mitochondrial Ca 2+ uptake has been shown to induce cell death in patients with Alzheimers disease (AD) ( 2+ uptake plays an important role in the pathophysiology of Parkinsons and possibly amyotrophic lateral sclerosis (ALS) ( Mitochondria participate in intracellular Ca 2+ signaling as modulators, buffers, and sensors ( 2+ and thus influence the shape, frequency, and amplitude of Ca 2+ spikes in the cytosol (Wacquier et al., 2016)

Adinortey MB, Galyuon IK, Asamoah NO

We outlined how curcumin modulates key inflammatory pathways and oxidative stress responses, and how it exerts broad-spectrum antimicrobial effects against oral pathogens

Cataracts can be caused by many factors, including radiation and diabetes, but the underlying cause is oxidative damage

Nevertheless, when a person whose intestinal barrier has been compromised by trauma, acute inflammatory conditions such as pancreatitis, burns, or surgery, increased endotoxin concentrations are present in the circulation [42, 56, 57]

Competency-based Preparation of Senior Medical Students for Residency Training: 2-year Cumulative Analysis of a Model Preparatory Course