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Nuclear p53 induces autophagy through the transcriptional activation of ATGs, lysosomal genes, and upstream regulators such as TFEB, contributing to tumor suppression and stress adaptation

This might suggest that catalases operate with kinetics that seemingly are impossibly faster than H 2 O 2 diffusion rates

The protein first protects developing sperm from oxidative stress damage to DNA as an antioxidant enzyme [2]

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378 Chaperone function and specificity can also be studied using CFE systems as has been done for the DnaK/DnaJ/GrpE chaperone system

doi: 10.1016/j.cortex.2024.07.004 61