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Curcumin, a component derived from turmeric and used in traditional Chinese medicine, has been discovered to cause iron accumulation, GSH depletion, and lipid peroxidation in non-small cell lung cancer (NSCLC) cells

At the same time, the antioxidant effect of VIC has been observed in preventing ROS and DNA damage

Nat Metab 6:200202 Olm E, Fernandes AP, Hebert C, Rundlf AK, Larsen EH, Danielsson O, Bjrnstedt M (2009) Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite