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Signs and symptoms [edit] LNS is characterized by three major hallmarks: neurologic dysfunction, cognitive and behavioral disturbances including self-mutilation, and uric acid overproduction (hyperuricemia)

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doi: 10.1016/j.phrs.2019.104623 148 LiuWFanTLiMZhangGGuoWYangXet al

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Mechanistic work shows it counters oxidative stress by boosting superoxide dismutase and catalase activities

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10.1038/ki.2012.393 Kidney Int

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In vivo acute toxicity and immunomodulation assessment of a novel nutraceutical in mice

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Krejcik J, Casneuf T, Nijhof IS, Verbist B, Bald J, Plesner T

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