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DOI:10.1038/ncb1975 [Google Scholar] Ni YQ, Liu YS

10.3390/antiox12071383 Antioxidants 36 GizachewS.EngidaworkE

If conditions are not favorable for thyroid hormone activity, such as extreme stressors like hibernation, starvation, and sepsis, then T4 is converted instead to reverse T3 (rT3) by D3, which is induced by the stress condition and localized to the outer plasma membrane of the cell