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Patients report dramatic benefits, but we cannot easily separate signal from placebo, concurrent rehab changes, rest, or natural recovery

FD has been further sub-classified into the postprandial distress syndrome (PDS) characterized by bothersome postprandial fullness or early satiation at least 3 days per week and the epigastric pain syndrome (EPS) characterized by bothersome epigastric pain or burning at least 1 day per week

Ovulation induction and successful pregnancy outcome in two patients with Prop1 gene mutations

McGregor JE, et al

How can the clinician find an appropriate balance between providing adequate pain relief while reducing the risk of developing tolerance, dependency, or abuse/misuse of opioids

H.WagenaarE.van DeemterL.et al (1994)