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But it's important to note that the subjects received abnormally high doses (10-20g per day), and supplement users who adhere to a manufacturers recommendations are highly unlikely to come near that amount.32 Several drug-drug interactions are possible, too

They are generally considered to have fewer side effects and be less dangerous than older-generation antidepressants, such as tricyclic antidepressants, because they specifically target the serotonin transporter, rather than affecting a wide range of neurotransmitters (Wang et al., 2018)

However, another study in the US did not replicate a large benefit