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Furthermore, toxic proteins present in Crotonis Fructus (Badou), such as croton protein I and II, not only exert direct cytotoxicity by inhibiting protein synthesis but also induce hemolysis by damaging erythrocyte membranes [61, 62]

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IEPB CFC instrument) and FACSCanto (BD Biosciences, San Jos, USA

Concentrations of GSH in various rat tissues (heart, kidneys, duodenum, jejunum, ileum, and colon) were quantitatively analyzed at 2.5, 8, and 24 h after administration

In particular, the relevance of the ATB 0,+ -mediated carnitine transport, in patients with PCD, may be explained considering that this protein is highly expressed in the intestine (Figure 2)

Simultaneously, in the extracellular pathway, drugs penetrate the nasal epithelium and enter the lamina propria, then move along the perineural spaces surrounding olfactory and trigeminal axons, allowing both small and large molecules to reach the CNS