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Thus, this review aims to summary metabolic pathways of human RBCs, focusing on their pathophysiological relevance and their regulation in oxidative stress-related conditions

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SEAMARK: phase II study of first-line encorafenib and cetuximab plus pembrolizumab for MSI-H/dMMR BRAFV600E-mutant mCRC

GC-MS for metabolite profile We profiled the metabolic changes in organs and plasma using our previously published GC-MS method 49,58,59

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Vitamin C 500mg/5ml Injection Composition: **Active Ingredient:** Ascorbic Acid (Vitamin C) - 500 mg **Excipients:** Sodium Chloride (for isotonicity) Water for Injection Hydrochloric Acid (to adjust pH) Sodium Hydroxide (to adjust pH) #### Dosage: **Recommended Dosage:** The typical dosage for adults is 500 mg (1 vial of 5 ml) administered intravenously or intramuscularly