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Polypharmacotherapy is a major concern in the elderly (Hofer-Duckelmann 2012

Neuropathic Pain The IASP defines neuropathic pain as pain caused by a lesion or disease of the somatosensory nervous system. 8 This condition encompasses a number of etiologies, including diabetes, cancer, chronic alcohol consumption, herpes zoster infection, traumatic nerve injury, drug toxicity, and central processes including cerebrovascular accidents, spinal cord injuries, and multiple sclerosis

Nassan FL, Chiu YH, Vanegas JC, et al

341 BSO, a gamma-glutamylcysteine synthetase inhibitor, disrupts redox balance and sensitizes cancer cells to chemotherapy, 342 while Imexon generates ROS, causing DNA damage and apoptosis in multiple myeloma

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Investigation of adult-onset multiple acyl-CoA dehydrogenase deficiency associated with peripheral neuropathy