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Review supplementation If elevated B12 results from excessive supplementation: Discontinue or reduce high-dose supplements unless medically indicated For patients receiving therapeutic B12 injections for confirmed deficiency, continue treatment as prescribedelevated levels are expected after replacement therapy and do not indicate toxicity Review with GP to ensure supplementation remains appropriate 3

Published preclinical data in rodents suggests doses equivalent to 200mg+ in humans produce off-target effects on folate metabolism and S-adenosylmethionine (SAMe) pools

Too much or too little iron can lead to cell damage

Endocrine Reviews, 21(5), 579-607

Evidence in one sentence: Both delivery systems are biologically plausible and supported by limited human biomarker or pharmacokinetic data, but neither has been proven superior for meaningful clinical outcomes

It can seriously reduce the musculoskeletal pain of your fibromyalgia, and youll find that it can improve your quality of life