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GSH being regarded as the main cellular antioxidant that acts as determining factor of the cellular redox state by regulating various redox signaling by reacting with ROS that is produced in response to various stresses thereby acting as a major scavenger 50,51

In summary, growing evidence underscores that gut microbiota dysbiosis plays a pivotal role in both the development and outcome of ischemic stroke through immune, barrier, and metabolic pathways, suggesting that restoring gut microbial balance could become an essential strategy for stroke prevention and recovery

Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-B

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