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doi: 10.7759/cureus.26735 23 LuytCEBrchotNDemondionPJovanovicTHkimianGLebretonGet al

(70) found higher 17,20-lyase activity of CYP17A1 based on metabolite ratios, around 150% higher in boys with ASD, as well as a higher DC ratio, suggesting a trend towards increased DHEA production over cortisol

Funding This work was supported by the National Natural Science Foundation of China (NSFC, 82472266), the National Key R&D Program of China (2023YFE0116000, 2023YFC2308300, 2023YFC2308302), the Beijing Natural Science Foundation (Z220018, L222068), the Scientific Research Project of Beijing Youan Hospital-CCMU 2022 (BJYAYY-YN2022-18), and the Beijing Key Laboratory for HIV/AIDS Research (BZ0089)

doi: 10.1016/j.lpm.2017.10.006 108 BessmanNJMathieuJRRRenassiaCZhouLFungTCFernandezKCet al

When an artificial joint is implanted in the body, degradation of the prosthesis is inevitable due to different physical and chemical effects such as mechanical stress, fretting, or fatigue corrosion, leading to the generation of metal particles with different diameters

Persistent fatigue or malaise : Whilst non-specific, unexplained tiredness may indicate liver dysfunction, particularly when accompanied by other symptoms