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mTOR was identified in the mid-1990s through biochemical isolation using a rapamycin-FKBP12 complex and by yeast two-hybrid analysis (8891)

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Moreover, mice with systemic knockout of SLC25A39 (including the heart) exhibited severe anemia, a complete lack of red blood cells, and iron overload [62]

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Furthermore, the regulatory effects of TCM on mTOR-related pathways in the context of DKD warrant further exploration and investigation