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Heme oxygenase-1 as a target for drug discovery

[DOI] [PMC free article] [PubMed] [Google Scholar] 311.Quintanilha AT

PRDX6 selectively binds oxidized phospholipids, becomes membrane-associated, and executes coordinated membrane repair through reductive detoxification, iPLA 2 -mediated deacylation, and LPCAT-dependent reacylation with non-oxidized fatty acids

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

36 The frequency and diversity with which hydrogen-producing mechanisms have occurred along the phylogenic tree suggest an inherent biological requirement for H 2 across all domains of life

The most studied families include: Glutathione and other -glutamyl peptides