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However, mild/moderate zinc deficiency is more common than severe zinc deficiency and, in humans, is usually associated with growth retardation, male hypogonadism, skin changes, loss of appetite, loss of taste, mild weight loss, mental lethargy, abnormal dark adaptation, and delayed wound healing (59, 62)

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Although a satisfactory synergistic anti-HCC effect was observed with NFX and OXA in vitro, the mechanisms involved have not been fully elucidated

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