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Senomorphics: Modulating the Senescence-Associated Secretory Phenotype (SASP) Unlike senolytic therapies that aim to directly eliminate senescent cells, senomorphics work by modulating the senescence-associated secretory phenotype (SASP), which consists of pro-inflammatory cytokines, chemokines, growth factors, and extracellular matrix-degrading enzymes secreted by senescent cells

J.CadacioC.et al (2007)

However, without simultaneous reduction of obesity, the remarkable resistance to developing steatosis in hepatocyte Cul3-deficient mice paradoxically caused profound systemic insulin resistance

J Hematol Oncol 17:119

While you are developing your own system for self-injections, dont forget to implement an aseptic technique to reduce your risk for infection