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Brain iron homeostasis and mental disorders

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Recovery from ROS-induced toxicity was tested through MTT assay, in HeLa and SHSY-5Y cells pre-exposed to 10 M 3-AT for 15 min or 1 mM MPP + for 24 h respectively, followed by 250 M 15 min Sp treatment

Mitochondria-targeted antioxidant SkQT1 decreases trauma-induced neurological deficit in rat and prevents amyloid--induced impairment of long-term potentiation in rat hippocampal slices

Long-term ASK1 targeting resulted in diminished net antifibrotic effect, but the progression to liver cirrhosis and cancer in BALBc/ Mdr2 -/- mice was effectively inhibited