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evidence is preclinical and investigational only

More than 1,000 genes have been linked to ASD, but none have been found to account for more than 1% of cases ( This article reviews the current state of research on oxidative stress in ASDs, focusing on the mechanism of oxidative stress, biological analysis of oxidative stress biomarkers, and antioxidant-based therapy methods

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Broadly speaking, by sensing altered homeostasis and tissue damage, cells of the innate immune system may contribute in many ways to initiation and amplification of inflammatory events leading to fibrosis [91]

(2003) An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells Br