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Recognition of PAMPs or DAMPs triggers a cascade of events, called PAMP-triggered immunity (PTI), which includes ion fluxes across the plasma membrane, generation of ROS, activation of mitogen-activated protein kinases (MAPKs) and transcriptional activation of genes

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Commonly observed adverse effects include abdominal discomfort, bloating, flatulence, and diarrhea, which generally diminish as the hosts system acclimates to the microbial intervention (552)

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doi:10.1016/j.biopsych.2006.11.021 75 Lee, T.-M., Lee, K.-M., Lee, C.-Y., Lee, H.-C., Tam, K.-W