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On the other hand, statins are widely used drugs that inhibit serum cholesterol levels by suppressing 3-hydroxy-3-methylglutaryl-CoA reductase (Sirtori, 2014), thereby reducing the synthesis of mevalonate and cholesterol

In mitochondria, it was postulated to cleave RNA complementary to the light chain near the D-loop sites that mark the transition from RNA to DNA synthesis (Lee and Clayton, 1997)