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Goekkurt et al., 2009)

These Ctr1-deficient mice exhibited marked growth retardation and reduced survival rates early after birth, likely due to insufficient copper absorption and subsequent impairment of copper-dependent enzymes and proteins (18)

Salhotra, A., Shah, H

In addition, we investigated the impact of the mutational status of CLL cells on ferroptosis susceptibility and identified potential metabolic vulnerabilities that could enhance ferroptotic cell death

Second, analyses based on pooled data cannot examine sex-or age-specific effects, nor can stratified analyses be performed

The comparison with the crystal structure of GPX4 (PDB 6HN3) revealed that a modelated GpoA display orthologous residues that could conform the catalytic site of tis enzyme, including Gln 70 , Trp 124 and Asn 125 , but Cys 36 in the place of Sec 46 (Fig