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The main sources of intracellular H 2 O 2 are NADPH oxidases (NOXs) and dual-oxidases (DUOXs) 36,37,38 , in conjunction with superoxide dismutases (SOD), as well as at the mitochondrial electron transport chain (ETC) 39,40 highlighting an important aspect of mitochondria within wound healing 41

Multiple studies have also demonstrated the clinical relevance of the levels of estrogen to the risk and relapse rate of MS (109, 110)

Blood sampling was performed under ether anesthesia, and animals were euthanized by an overdose of 250 mg/kg sodium pentobarbital [1]

Another factor is the severity and type of symptoms they are experiencing