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overactivation of PARPs, such as during extensive genotoxic stress, can result in significant NAD + depletion and subsequent compromise of cellular energy homeostasis

LC-MS/MS Sample was applied to LC-MS/MS on the day of manufacture (LC) :Liquid chromatography (LC) was performed using the following steps: A: 0.2%(v/v) Mobile phase A: 0.2% (v/v) formic acid in water B: 0.2%(v/v) Mobile phase B: 0.2% (v/v) formic acid in acetonitrile : : : = 5:4:1(v/v/v)washing solution: methanol: acetonitrile: water = 5:4:1 (v/v/v) LC :The additional LC parameters are summarized in the table below: Liquid chromatography conditions used SCIEX 6600 :Data collection on a high resolution SCIEX 6600 instrument was performed as follows: TOF .Samples were injected as described above, separated by reverse phase chromatography, ionized and analyzed by a triple TOF mass spectrometer

PLoS ONE 9 , e91467 (2014)

The compound appears in research focused on tendon healing and ligament recovery

It helps the body detoxify chemicals and pollutants

In a rat study of Achilles tendon tears, BPC-157-treated animals regained near-normal tendon strength in weeks, compared with months in untreated groups