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These results show that BSO reduces viability of BL cell lines, while having no effect on control B cells (Fig

Intriguingly, all HANs (BAN, CAN, DBAN, TCAN), with the exception of DCAN, reduced the phosphorylation of H2AX showing that DNA breaks are not the cause of the arrest (Fig

3.7 Cuproptosis: a novel cell death pathway Cuproptosis is a newly discovered, unique form of cell death induced by the direct binding of copper ions to lipoylated proteins, disrupting the function of protein-associated iron-sulfur clusters and triggering cell death

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Microtubules serve as the track for axonal transport, and taxanes interrupt this in vitro , which may lead to neuropathy 43 (Figure 1)