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doi: 10.1097/MPG.0000000000003015, 4

(c)-(d) NIR-II imaging of lung tissue dissected from lung metastatic mice after 24 h post-injection of (100 nM) LJ-GSH

Metabolism Selinexor is metabolized by CYP3A4, multiple UDP-glucuronosyltransferases (UGTs) and glutathione S-transferases (GSTs)

Indeed, SH-SY5Y cells showed high GSH levels but exhibited very low GPx activity, whereas AGS cells had low GSH content but several isoforms of the GPx enzyme