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McMahon, B

Am J Hematol 2014;89:678-83

LGGs with NF1 mutations show greater T cell infiltration, whereas mesenchymal GBMs demonstrate substantial but often ineffective T cell presence

Importantly, combination of metformin and radiation significantly increased cell death, when compared to irradiated vehicle controls, highlighting the potential role for altered cell death in the metformin-mediated radiosensitisation of these cell lines

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