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Although some of the natural ingredients used in these patches, such as berberine, have shown in some studies to slightly increase GLP-1 levels, regulate blood sugar levels and promote weight loss 8 , their efficiency through transdermal methods is not yet proven and needs to be studied further 3

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Additionally, GHK was suggested to have potential action in reducing iron release from ferritin, a lipid peroxidation catalyst

In addition, excessive NEFAs lead to increasing lipid esterification and ceramide production, causing oxidative stress, and promoting the production of NO

I provide a shield for cellular macromolecules by fighting oxidative stress and neutralizing free radicals

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