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Based on statistical modeling, those participants with a serum B12 287pmol/L (who likely had adequate B12 status), serum MMA was low (i.e., 120nmol/L)

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After he died in 1984, other physicians and naturopaths took up prescribing "intravenous micronutrient therapy" with unsubstantiated health claims for treating fatigue, low energy, stress, anxiety, migraine, depression, immunocompromised, promoting weight loss, and more

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It's a good option for those looking to avoid high doses, but the daily serving of six large capsules may be a drawback for some, and the inclusion of vitamin K means it may not be appropriate if you're on blood thinners