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Brain 139 , 431443 (2016)

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Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria

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The intrinsic factor binds to the B12, that by this time has been freed from the food which carried it to the ileum (the food is the extrinsic factor by the way)to make a mixture of B12 and intrinsic factor known as "B12/IF complex"

This interaction has the potential to increase intracellular zinc, thereby enhancing prion conformation (56)